Principal Engineer- Advanced Operations

stryker· Stryker Employment Company, LLC
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📍 Irvine, CaliforniaFull time💰 USD 136K–226K

About this role

Work Flexibility: Onsite

The Principal Advanced Operations Engineer - Technical Lead is a senior technical leader responsible for driving manufacturing excellence, process development, technology transfer, and operational readiness for new product launches. As the primary manufacturing and operations engineering authority within R&D, this role leads cross-functional initiatives to enhance manufacturability, improve operational performance, and accelerate commercialization. The position requires expertise in manufacturing engineering, process validation, lean manufacturing, automation, quality systems, and project leadership.

Key Responsibilities:

  • Serve as the technical lead for advanced manufacturing and operations engineering initiatives supporting new product development, implementation, and commercialization.

  • Provide strategic direction for manufacturing process development, optimization, scale-up, operational readiness, and technology transfer to production.

  • Partner with R&D throughout the product development lifecycle to ensure manufacturability and scalability and drive engineering best practices through Design for Manufacturing (DFM) and Design for Assembly (DFA).

  • Lead continuous improvement initiatives focused on safety, quality, delivery, and cost performance.

  • Lead equipment qualification and process validation activities, including IQ/OQ/PQ execution.

  • Collaborate with Quality, Supply Chain, Manufacturing, Regulatory Affairs, and R&D to deliver successful product launches and process implementations.

  • Lead multidisciplinary project teams, influence organizational stakeholders, and drive alignment on technical and operational decisions.

  • Provide technical expertise in lean manufacturing, Six Sigma, advanced manufacturing processes, automation, and process validation methodologies.

Qualifications:

Required:

  • Bachelor's degree in Engineering or related field.

  • 8+ years of progressive experience in manufacturing engineering, operations, or new product implementation.

  • 5+ years leading complex technical projects and cross-functional teams.

Preferred:

  • Master's degree.

  • Experience in regulated industries.

  • Experience with process validation, equipment qualification, lean manufacturing, and continuous improvement methodologies.

  • Experience influencing both leaders and individual contributors cross functionally.

  

 

United States of America Pay Ranges:

  • US15: $135,700 - $226,200 USD Annual

  

 

Travel Percentage: 20%

Stryker Corporation is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, or protected veteran status. Stryker is an EO employer – M/F/Veteran/Disability.

Stryker Corporation will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information.

Frequently Asked Questions

What is the salary for the Principal Engineer- Advanced Operations role at stryker?
The listed salary for this Principal Engineer- Advanced Operations position at stryker is USD 136K–226K. This is an Full time role.
Where is the Principal Engineer- Advanced Operations position at stryker located?
This Principal Engineer- Advanced Operations role at stryker is based in Irvine, California. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Is the Principal Engineer- Advanced Operations role at stryker full-time or part-time?
This is listed as a Full time position. It is posted as a Principal Engineer- Advanced Operations role in the Stryker Employment Company, LLC department at stryker.
Which team or department does the Principal Engineer- Advanced Operations at stryker belong to?
This Principal Engineer- Advanced Operations position is part of the Stryker Employment Company, LLC department at stryker. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Principal Engineer- Advanced Operations position at stryker?
Click the "Apply Now" button on this page. You will be redirected to stryker's official application portal hosted on workday where you can submit your application directly.
When was the Principal Engineer- Advanced Operations job at stryker posted?
This Principal Engineer- Advanced Operations position at stryker was posted on Aug 31, 2026. Apply as soon as possible — early applications are often reviewed first.
Principal Engineer- Advanced Operations
stryker · 💰 USD 136K–226K
Apply for this role ↗

You'll be redirected to stryker's official application page on Workday.