Shift Supervisor, Research Operations

lilasciences· Autonomous Science Platform
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📍 Cambridge, MA USA💰 USD 119K–182K

About this role

Your Impact at LILA

Lila's Research Operations team runs the automated lab workflows that power our science. As a Shift Supervisor, you own the reliable execution of those workflows across your shift, serve as the technical lead for the engineers running them, and directly manage and develop a team of Research Operations engineers. You are the first point of accountability for run quality, the first source of operational guidance for engineers on shift, and a critical link between the bench and the automated systems behind our science.

This is an on-site, second-shift role with working hours of 2:00 PM-10:00 PM. You'll lead, coach, and develop some of the most energetic and brilliant minds in Research Operations, creating an environment where they can grow, take ownership, and do their best work.

This role is ideal for someone who thrives on operational ownership, takes pride in process discipline, enjoys developing others, and knows how to keep a team and workflows running smoothly in a fast-paced, high-throughput environment.

What You'll Be Building

  • Own the safe, reliable execution of automated lab workflows across your shift, meeting quality, throughput, and operational performance targets
  • Serve as the technical lead for engineers on shift, providing real-time guidance, prioritization, and workflow coordination
  • Manage, coach, and develop direct reports, setting clear expectations, providing actionable feedback, and building technical capability and ownership across the team
  • Monitor run performance and system health in real time, independently resolving common issues, and escalating complex problems appropriately
  • Manage accurate shift handoff documentation in real time, ensuring seamless continuity with the incoming team
  • Flag QC/QA deviations promptly and accurately, documenting observations with high attention to detail
  • Partner with scientific, engineering, and automation teams to troubleshoot workflow challenges and improve operational performance, including ongoing relationships with scientific leads
  • Support tech transfer by validating automated workflows against manual processes and partnering with cross-functional teams to resolve process gaps and improve robustness

What You'll Need to Succeed

  • 5+ years of hands-on experience in lab automation, research operations, high-throughput screening, or a closely related technical environment
  • Prior formal people-management experience with direct reports in a laboratory, technical, or operations environment, including setting expectations, providing feedback, coaching and developing team members, and driving accountability for performance
  • Experience operating and troubleshooting automated liquid handling platforms (Hamilton, Lynx, Echo, or similar) in a production or research setting
  • Experience leading and coordinating workflow execution in a team setting, including providing direction to engineers, managing competing priorities, and maintaining operational continuity in real time
  • Strong foundational knowledge of the scientific basis for assay design, execution, and interpretation
  • Experience identifying operational issues, performing root-cause investigation, and driving issues to resolution
  • Clear, concise communicator with the ability to collaborate effectively across Research Operations, scientific, engineering, and LabOps teams

Bonus Points For

  • Degree in Biology, Chemistry, Engineering, Biotechnology, or a related field, or equivalent technical training and hands-on experience
  • Prior experience managing a shift or technical team in a highly automated or high-throughput laboratory environment
  • Experience improving production protocols, supporting tech transfer, or validating workflows from manual bench execution to automated platforms
  • Familiarity with QC/QA systems, deviation management, SOP development, and continuous improvement methodologies (Lean, 5S, Kaizen)
  • Familiarity with electronic lab notebooks (ELN), LIMS, or other laboratory operations software platforms
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Compensation

We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.

U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.

Expected Base Salary Range
$118,800$182,400 USD

About LILA

Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.

LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.

Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.

We’re All In

Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.

A Note to Agencies

Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.

Frequently Asked Questions

What is the salary for the Shift Supervisor, Research Operations role at lilasciences?
The listed salary for this Shift Supervisor, Research Operations position at lilasciences is USD 119K–182K. This is an full-time role.
Where is the Shift Supervisor, Research Operations position at lilasciences located?
This Shift Supervisor, Research Operations role at lilasciences is based in Cambridge, MA USA. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Which team or department does the Shift Supervisor, Research Operations at lilasciences belong to?
This Shift Supervisor, Research Operations position is part of the Autonomous Science Platform department at lilasciences. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Shift Supervisor, Research Operations position at lilasciences?
Click the "Apply Now" button on this page. You will be redirected to lilasciences's official application portal hosted on greenhouse where you can submit your application directly.
When was the Shift Supervisor, Research Operations job at lilasciences posted?
This Shift Supervisor, Research Operations position at lilasciences was posted on Jul 1, 2026. Apply as soon as possible — early applications are often reviewed first.
Shift Supervisor, Research Operations
lilasciences · 💰 USD 119K–182K
Apply for this role ↗

You'll be redirected to lilasciences's official application page on Greenhouse.