Senior Staff AI Engineer - Global Infrastructure

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About this role

The Enterprise Technology Services organization partners with every part of the American Express business to power the company’s growth and innovation with trust and efficiency, and drive competitive differentiation with speed. We support the delivery and operations of technology, digital, and data capabilities, platforms, and services globally. Specifically, our team is responsible for the company’s technology engineering, architecture, and infrastructure, providing 24x7 support to ensure an uninterrupted, high-quality experience for customers and colleagues. We also provide product management for core enterprise platforms, and lead technology risk and information security, enterprise data governance and platforms, digital product and design, and enterprise AI platforms on behalf of the company

Senior Staff AI Engineer leads enterprise-scale AI architecture and implementation across infrastructure and agentic AI systems. The role sets technical direction, ensures scalable, reliable, secure, and responsible AI platforms, mentors senior technical talent, and drives continuous improvement in AI engineering practices and platform capabilities.

  • Serves as a senior technical authority for enterprise-scale AI systems with significant strategic and long-term business impact
  • Defines architecture and engineering patterns for agentic AI, retrieval/grounding, model integration, inference platforms, observability, evaluation, and safety
  • Leads resolution of complex and ambiguous technical challenges, balancing performance, cost, scalability, security, safety, and regulatory constraints
  • Shapes long-term AI engineering strategy across platforms, tools, and system design approaches
  • Guides multiple cross-team AI initiatives to ensure coherent architecture, integration, and alignment across domains
  • Leads technical and architectural reviews, setting standards for engineering excellence and consistent implementation
  • Partners with Product, Data Engineering, Cloud Infrastructure, Architecture, Risk, and Cybersecurity leaders to align AI solutions with enterprise priorities and governance requirements
  • Evaluates emerging AI technologies and translates them into scalable, enterprise-ready capabilities
  • Mentors Staff and Senior Engineers, raising organizational technical capability and developing future technical leaders

Education and Knowledge

  • MS/PhD in Artificial Intelligence, Machine Learning, Computer Science, or related discipline preferred
  • Deep knowledge of machine learning and deep learning systems, including model architectures, training, evaluation, and optimization
  • Advanced knowledge of Generative AI and LLM ecosystems, including embeddings, fine-tuning, prompt design, retrieval-augmented generation, and inference at scale
  • Strong understanding of AI infrastructure, including GPU platforms, accelerated compute, workload scheduling, capacity optimization, model serving, and inference performance
  • Advanced understanding of agentic AI design, including planning, reasoning, tool use, memory, multi-agent coordination, and autonomy controls
  • Strong foundation in distributed systems, cloud-native architecture, Kubernetes, APIs, microservices, event-driven design, observability, and platform reliability
  • Knowledge of DevOps and CI/CD platforms such as Harness, including automated deployment, environment promotion, governance, and operational controls
  • Knowledge of enterprise AI governance, including model risk management, explainability, bias detection, safety, and regulatory compliance

 

Work Experience

  • 12+ years of experience in AI/ML engineering, AI infrastructure, platform engineering, data engineering, or related fields, with a track record of delivering complex production systems at scale
  • Proven experience architecting end-to-end AI/ML platforms across data pipelines, training, deployment, serving, monitoring, and inference optimization
  • Experience designing and operating GPU-based AI infrastructure, including accelerated compute platforms, workload scheduling, utilization optimization, capacity management, and performance tuning
  • Experience with cloud-native and Kubernetes-based platforms supporting training, batch workloads, inference, orchestration, observability, reliability, and cost efficiency
  • Hands-on experience with Python and modern AI/ML frameworks such as PyTorch, TensorFlow, Scikit-learn, Hugging Face, and related tooling
  • Deep experience with agentic AI systems, including planning, tool use, memory, evaluation, retrieval, embeddings, vector databases, and agent frameworks
  • Experience leading complex cross-functional technical initiatives and influencing architecture and engineering direction across teams without direct authority
  • Demonstrated ability to mentor and develop engineers at all levels, including Staff-level engineers
  • Experience working in regulated environments such as financial services, including AI governance, risk management, and compliance considerations 

    Depending on factors such as business unit requirements, the nature of this position, cost and applicable laws, American Express may provide visa sponsorship for certain positions. 

At American Express, our culture is built on a 175-year history of innovation, shared values and Leadership Behaviors, and an unwavering commitment to back our customers, communities, and colleagues. From delivering differentiated products to providing world-class customer service, we operate with a strong risk mindset, ensuring we continue to uphold our brand promise of trust, security, and service.

As part of Team Amex, you’ll experience our powerful backing with comprehensive support for your holistic well-being and many opportunities to learn new skills, develop as a leader, and grow your career. Here, your voice and ideas matter, your work makes an impact, and together, you will help us define the future of American Express.

Frequently Asked Questions

Is the salary disclosed for the Senior Staff AI Engineer - Global Infrastructure position at American Express?
The salary for this Senior Staff AI Engineer - Global Infrastructure role at American Express is not publicly listed. Click "Apply Now" to learn more about the compensation package on their official careers page.
Where is the Senior Staff AI Engineer - Global Infrastructure position at American Express located?
This Senior Staff AI Engineer - Global Infrastructure role at American Express is based in New York, NY, United States, Phoenix, AZ, United States, Sunrise, FL, United States. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Is the Senior Staff AI Engineer - Global Infrastructure role at American Express full-time or part-time?
This is listed as a Full time position. It is posted as a Senior Staff AI Engineer - Global Infrastructure role at American Express.
How do I apply for the Senior Staff AI Engineer - Global Infrastructure position at American Express?
Click the "Apply Now" button on this page. You will be redirected to American Express's official application portal hosted on oraclecloud where you can submit your application directly.
When was the Senior Staff AI Engineer - Global Infrastructure job at American Express posted?
This Senior Staff AI Engineer - Global Infrastructure position at American Express was posted on Oct 2, 2026. Apply as soon as possible — early applications are often reviewed first.
Senior Staff AI Engineer - Global Infrastructure
American Express
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