Senior Scientist

repligen· Repligen Corp
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📍 Lebanon, NHFull time
Full timeRepligen Corp

About this role

Lead the design and optimization of next-generation affinity purification technologies for a wide range of biopharmaceutical modalities. This role combines high-throughput experimentation, data-driven process development, and cross-functional collaboration to deliver innovative purification solutions that accelerate bioprocessing performance and enable partner success.


“This role is expected to model our Leadership Behaviors—Integrity & Compliance, Customer Focus, Collaboration, Courage, Team Empowerment, and Accountability & Results—in all aspects of work.”

Key Responsibilities

  • Design, develop, and optimize affinity chromatography–based purification processes for diverse biopharmaceutical modalities
  • Execute high-throughput chromatographic screening and apply DOE methodologies to accelerate process development
  • Analyze, interpret, and communicate complex datasets to drive decision-making and support partner adoption of new technologies
  • Collaborate cross-functionally with internal teams (chemistry, analytics, commercial) to deliver integrated purification solutions
  • Contribute to multiple development programs, ensuring timely execution and high-quality scientific output
  • Innovate and propose novel approaches to improve purification performance, selectivity, and scalability
  • Engage with external biopharma partners as a technical expert and scientific collaborator

Qualifications

  • MS or PhD in Biochemistry, Chemical Engineering, Biochemical Engineering, or related field
  • Minimum of 5 years of hands-on experience in downstream processing and protein purification; including FPLC
  • Experience across multiple modalities (e.g., proteins, enzymes, vaccines, VLPs, gene therapy vectors)
  • Expertise in chromatography method development, including automated/high-throughput systems
  • Strong proficiency with Design of Experiments (DOE) for process optimization
  • Working knowledge of analytical techniques (e.g., purity/impurity analysis, potency, stability assays)
  • Broad scientific understanding spanning separations, protein chemistry, and bioprocessing
  • Strong communication skills with the ability to translate data into clear, actionable insights
  • Self-motivated, collaborative, and effective in a fast-paced, innovation-driven environment

Our mission is to inspire advances in bioprocessing as a trusted partner in the production of biologic drugs that improve human health worldwide. Focused on cost and process efficiencies, we deliver innovative technologies and solutions that help set new standards in bioprocessing. The estimated salary range for this role, based in the United States of America is $115,000/yr. -$145,000/yr.

Compensation decisions are dependent on several factors including, but not limited to an individual's qualifications, location, internal equity, and alignment with market data. Additionally, employees are eligible to participate in one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits such as paid time off, health/dental/vision, retirement benefits and flexible spending accounts. All compensation and benefits information will be confirmed in writing at the time of offer.

Frequently Asked Questions

Is the salary disclosed for the Senior Scientist position at repligen?
The salary for this Senior Scientist role at repligen is not publicly listed. Click "Apply Now" to learn more about the compensation package on their official careers page.
Where is the Senior Scientist position at repligen located?
This Senior Scientist role at repligen is based in Lebanon, NH. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Is the Senior Scientist role at repligen full-time or part-time?
This is listed as a Full time position. It is posted as a Senior Scientist role in the Repligen Corp department at repligen.
Which team or department does the Senior Scientist at repligen belong to?
This Senior Scientist position is part of the Repligen Corp department at repligen. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Senior Scientist position at repligen?
Click the "Apply Now" button on this page. You will be redirected to repligen's official application portal hosted on workday where you can submit your application directly.
When was the Senior Scientist job at repligen posted?
This Senior Scientist position at repligen was posted on Aug 17, 2026. Apply as soon as possible — early applications are often reviewed first.
Senior Scientist
repligen
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