Associate Director, Talent Acquisition Operations & Programs
dynetherapeutics
Senior Manager, US Medical Affairs
dynetherapeutics· 4000US - Medical Affairs - US
About this role
Company Overview:
Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for facioscapulohumeral muscular dystrophy (FSHD), Pompe disease and multiple DMD mutations. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.
Role Summary:
The Senior Manager, US Medical Affairs supports execution of Dyne’s US Medical Affairs strategy for the Duchenne Muscular Dystrophy (DMD) program. This role contributes to critical launch readiness activities and supports the planning and delivery of US Medical initiatives, including KOL engagement, congress execution, medical education efforts, and cross-functional coordination.
The Senior Manager operates as both a scientific and operational contributor, helping prepare the US Medical organization for anticipated DMD program needs. This role partners closely with Medical Science Liaisons (MSLs), Global Medical Affairs, and cross-functional stakeholders to ensure medical activities are high-quality, compliant, and impactful.
This role is based in Waltham, MA.
Primary Responsibilities Include:
Medical Strategy Execution & Launch Readiness
- Supports execution of US Medical Affairs tactical plans for the DMD program
- Assists in implementing scientific platform materials, congress planning, and medical education initiatives
- Contributes to cross-functional launch readiness activities to ensure alignment with program milestones
- Supports development and deployment of DMD-focused scientific materials, disease state education resources, and field medical tools
Field Medical & KOL Engagement
- Partners with the US MSL team to support KOL identification, engagement planning, insight gathering, and field metric tracking
- Translates field insights into actionable recommendations for Medical Affairs and cross-functional teams
- Tracks and monitors field activity and engagement effectiveness
Scientific Materials & Medical Review
- Contributes to development of scientific materials, field tools, and educational content
- Provides Medical review for promotional materials through the Promotional Review Committee (PRC)
- Maintains deep and current scientific knowledge in DMD and Dyne’s therapeutic platform
Congress & External Engagements
- Supports planning and execution of medical congresses, including onsite activities aligned to DMD milestones
- Coordinates logistics and execution of US advisory boards and expert engagements
Cross-Functional Collaboration & Compliance
- Partners with Patient Advocacy, Market Access, and Commercial teams to support aligned medical activities
- Ensures all activities comply with US regulatory, legal, and compliance standards
- Models Dyne’s core values through collaboration, accountability, and scientific integrity
Education and Skills Requirements:
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Advanced scientific or clinical degree required (PhD, PharmD, MD, or equivalent)
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7+ years of relevant Medical Affairs experience in pharmaceutical or biotechnology industry
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Rare disease experience preferred; neuromuscular disease experience a plusExperience supporting US-based medical tactics, congress activities, or field medical programs
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Strong scientific acumen with ability to translate clinical data for diverse audiences
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Excellent written and verbal communication skills
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Ability to operate effectively in a fast-paced, evolving environment with competing priorities
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Demonstrated ability to build collaborative relationships with internal and external
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to travel up to 25%, including occasional overnight and weekend travel
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Positive team orientation with strong alignment to Dyne’s Core Values
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Passion for improving the lives of patients with neuromuscular diseases
#LI-Onsite
MA Pay Range
$165,000—$190,000 USD
The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.
The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.
Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Frequently Asked Questions
What is the salary for the Senior Manager, US Medical Affairs role at dynetherapeutics?
The listed salary for this Senior Manager, US Medical Affairs position at dynetherapeutics is USD 165K–190K. This is an full-time role.
Where is the Senior Manager, US Medical Affairs position at dynetherapeutics located?
This Senior Manager, US Medical Affairs role at dynetherapeutics is based in Waltham, MA. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Which team or department does the Senior Manager, US Medical Affairs at dynetherapeutics belong to?
This Senior Manager, US Medical Affairs position is part of the 4000US - Medical Affairs - US department at dynetherapeutics. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Senior Manager, US Medical Affairs position at dynetherapeutics?
Click the "Apply Now" button on this page. You will be redirected to dynetherapeutics's official application portal hosted on greenhouse where you can submit your application directly.
When was the Senior Manager, US Medical Affairs job at dynetherapeutics posted?
This Senior Manager, US Medical Affairs position at dynetherapeutics was posted on Jun 29, 2026. Apply as soon as possible — early applications are often reviewed first.
Senior Manager, US Medical Affairs
dynetherapeutics · 💰 USD 165K–190K
You'll be redirected to dynetherapeutics's official application page on Greenhouse.