Senior Manager, Commercial Strategy, TMTT

edwards· Edwards Lifesciences LLC
Apply Now ↗
📍 USA-California-Hybrid📍 USA - California – IrvineFull time💰 USD 139K–196K

About this role

Patients with mitral and tricuspid heart valve disease often have complex conditions with limited treatment options. Our Transcatheter Mitral and Tricuspid Therapies (TMTT) business unit is boldly pursuing an innovative portfolio of technologies to address a patient’s unmet clinical needs. It’s our driving force to help patients live longer and healthier lives. Join us and be part of our inspiring journey.


As the Senior Manager, Commercial Strategy you will apply subject-matter expertise and guidance to advance sales strategy & operations activities and leadership decision making. Serves as a bridge between commercial strategy and execution by translating business needs into actionable insights and operational solutions.


This role is onsite / hybrid, based out of the Edwards Corporate Headquarters in Irvine, CA.


How you'll make an impact:

Strategic Planning & Execution

  • Foster a culture of accountability, continuous improvement, and operational excellence.
  • Partner with Commercial Operations leadership to define and execute annual and long-range strategic priorities.
  • Translate executive objectives into measurable action plans, governance structures, and performance metrics.
  • Drive execution of high-priority business initiatives and ensure cross-functional accountability.
  • Monitor progress against strategic goals and proactively identify risks, dependencies, and mitigation plans.
  • Lead special projects and enterprise initiatives on behalf of Commercial Operations leadership.

Executive Leadership Support

  • Prepare executive briefings, business reviews, leadership-level materials, and strategic presentations.
  • Facilitate leadership team meetings, operating reviews, and business planning sessions.
  • Drive decision-making processes by synthesizing data, stakeholder input, and business insights.
  • Manage leadership communications and ensure organizational alignment around key priorities.

Organizational Effectiveness

  • Establish operational rhythms, governance models, and management systems that improve execution efficiency.
  • Improve cross-functional collaboration and remove organizational barriers to execution.
  • Lead operating cadence processes including QBRs, MBRs, annual sales planning, and strategic reviews.
  • Identify opportunities to streamline processes and improve organizational performance. Support integration of new technologies, processes, and organizational capabilities.

Business Performance & Analytics

  • Partner with analytics and business intelligence teams to monitor critical KPIs and business outcomes.
  • Develop performance reviews to support decision-making.
  • Ensure leadership visibility into key business risks, opportunities, and emerging market dynamics.

Leadership Team Operations

  • Own leadership team governance and meeting effectiveness.
  • Track decisions, commitments, and executive action items to ensure follow-through.
  • Facilitate alignment across functional leaders and support escalation management when needed.


What you’ll need (required):

  • Bachelor's Degree in related field or equivalent work experience based on Edwards criteria required
  • Minimum ten (10) years’ progressive experience in sales operations; sales strategy; and /or sales business intelligence required
  • Ability to travel up to 15% (occasional for QBR and Leadership Meetings)

What else we look for (preferred):

  • Advanced proficiency in analytical tools such as Excel, Oracle, JDE, MIDAS, Tableau, ELBIS, Salesforce.com, or QlikView preferred
  • Proficient with Microsoft Office applications (Outlook, Excel, Power Point, Word, Copilot etc)
  • Knowledgeable across sales operations, marketing, finance, and commercial data systems preferred
  • Proven project management experience, with the ability to manage timelines, priorities, and cross-functional deliverables
  • Professional written, verbal, and interpersonal communication skills, including the ability to influence, negotiate, and build effective relationships
  • Demonstrated ability to think strategically, connect insights across the business, and recommend practical solutions
  • Sound judgment and decision-making skills, including the ability to move work forward when consensus is not immediate High level credibility, integrity, and a track record of delivering results
  • Strong analytical, organizational, and problem-solving skills with high attention to detail
  • Ability to work effectively with stakeholders at all levels and escalate issues appropriately
  • Ability to manage competing priorities in a fast-paced environment
  • Experience supporting projects and partnering with project managers, sales strategy, and operations teams
  • Ability to provide task-level guidance to outsourcing partners or external vendors.
  • Commitment to following all company policies and requirements, including Environmental Health & Safety guidelines




Aligning our overall business objectives with performance, we offer competitive salaries, performance-based incentives, and a wide variety of benefits programs to address the diverse individual needs of our employees and their families.

For California, the base pay range for this position is $139,000 - $196,000 (highly experienced).

The pay for the successful candidate will depend on various factors (e.g., qualifications, education, prior experience).  Applications will be accepted while this position is posted on our Careers website.  






Edwards is an Equal Opportunity/Affirmative Action employer including protected Veterans and individuals with disabilities.

Frequently Asked Questions

What is the salary for the Senior Manager, Commercial Strategy, TMTT role at edwards?
The listed salary for this Senior Manager, Commercial Strategy, TMTT position at edwards is USD 139K–196K. This is an Full time role.
Where is the Senior Manager, Commercial Strategy, TMTT position at edwards located?
This Senior Manager, Commercial Strategy, TMTT role at edwards is based in USA-California-Hybrid, USA - California – Irvine. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Is the Senior Manager, Commercial Strategy, TMTT role at edwards full-time or part-time?
This is listed as a Full time position. It is posted as a Senior Manager, Commercial Strategy, TMTT role in the Edwards Lifesciences LLC department at edwards.
Which team or department does the Senior Manager, Commercial Strategy, TMTT at edwards belong to?
This Senior Manager, Commercial Strategy, TMTT position is part of the Edwards Lifesciences LLC department at edwards. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Senior Manager, Commercial Strategy, TMTT position at edwards?
Click the "Apply Now" button on this page. You will be redirected to edwards's official application portal hosted on workday where you can submit your application directly.
When was the Senior Manager, Commercial Strategy, TMTT job at edwards posted?
This Senior Manager, Commercial Strategy, TMTT position at edwards was posted on Sep 26, 2026. Apply as soon as possible — early applications are often reviewed first.
Senior Manager, Commercial Strategy, TMTT
edwards · 💰 USD 139K–196K
Apply for this role ↗

You'll be redirected to edwards's official application page on Workday.