Scientist, Biology
medraai
Scientist, Biology
alector· Biology
About this role
Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused on developing treatments for some of the most challenging diseases facing our society. By harnessing advancements in genetics, immunology and neuroscience, we are pioneering the development of potential therapies to counteract the devastating progression of neurodegeneration. We are supported in this mission by experienced and accomplished scientists and clinicians, a novel portfolio of programs, leading healthcare investors, and pharma company partners, who share in our commitment to bettering the lives of patients and realizing a world where we make brain disorders history.
As a Scientist on our Biology team, you will design and execute in vitro studies and analytical assays that help us evaluate potential therapeutics for neurodegenerative diseases. You will work with advanced cellular models, process in vivo and in vitro samples, and generate high-quality data that inform pharmacokinetics/pharmacodynamics (PK/PD), efficacy, safety, proof-of-concept (POC), and mechanism-of-action (MOA) studies.
You’ll collaborate closely with colleagues across Biology, ADPE, and Preclinical teams to advance our programs. We value scientific curiosity, thoughtful experimentation, and the ability to adapt as our science and priorities evolve.
Key Goals and Accountabilities
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Advance our therapeutic programs! Design and execute in vitro pharmacology studies using iPSC-derived cellular models, including induced neurons, induced microglia, and co-culture and triple-culture systems.
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Build disease-relevant models! Develop and optimize cellular models of neurodegenerative disease, including Alzheimer’s disease, to enable POC and MOA studies.
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Generate decision-driving data! Collect and process cell lysates, media, rodent brain, and other biological samples and perform downstream biochemical and cellular analyses.
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Turn experiments into shared insights! Analyze, interpret, document, and communicate results while maintaining accurate experimental records, protocols, and data in our electronic lab notebook.
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Accelerate how we do science! Collaborate across Biology, ADPE, and Preclinical teams while identifying opportunities to integrate innovative technologies, especially AI, to expedite programs, improve scientific workflows, and save valuable resources.
Required Qualifications
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PhD in Neuroscience, Immunology, Biology, or a related scientific discipline.
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Hands-on experience with cell culture, including iPSC-derived and/or primary rodent neuronal models.
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Experience with biochemical and cellular techniques such as immunoblotting, ELISA, MSD, immunocytochemistry, flow cytometry/FACS, or immunohistochemistry.
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Demonstrated ability to analyze and interpret experimental data and clearly communicate scientific findings.
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You are an active user of large language models (LLMs) and have a strong interest in evolving AI technologies and how they can improve scientific research and productivity.
Preferred Qualifications
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Experience working in a biotechnology or pharmaceutical research environment.
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Experience developing or optimizing cellular models of neurodegenerative disease.
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Familiarity with confocal microscopy and neurohistology techniques.
At Alector, our vision is bold, people are our priority, and our values are at the core of everything we do. Our dynamic and flexible environment encourages our teams to experiment, take ownership of decisions, and question convention to solve complex problems. We value shared wins, perseverance, and a growth mindset, which drives us forward, together.
Among the things you'll discover at Alector from your very first day are our committed and driven colleagues, a bold company vision, and new, modern offices designed to inspire innovation and collaboration in South San Francisco, right at the heart of Biotech Bay. Our benefits are thoughtfully designed around Alectorians and their loved ones and include flexible hybrid work options, competitive compensation, and comprehensive and unique benefits that enhance your health and well-being. Come join us!
We believe that hard-working teams include people from a wide variety of backgrounds and experiences who can challenge each other’s assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, sexual orientation, age, marital status, veteran status, or disability status, or any other characteristics protected under applicable federal, state, or local laws.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, perform essential job functions, and receive other benefits and privileges of employment. Please contact us to request accommodation.
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Frequently Asked Questions
What is the salary for the Scientist, Biology role at alector?
The listed salary for this Scientist, Biology position at alector is USD 145K–155K. This is an Full time Exempt role.
Where is the Scientist, Biology position at alector located?
This Scientist, Biology role at alector is based in South San Francisco, CA. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Is the Scientist, Biology role at alector full-time or part-time?
This is listed as a Full time Exempt position. It is posted as a Scientist, Biology role in the Biology department at alector.
Which team or department does the Scientist, Biology at alector belong to?
This Scientist, Biology position is part of the Biology department at alector. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Scientist, Biology position at alector?
Click the "Apply Now" button on this page. You will be redirected to alector's official application portal hosted on lever where you can submit your application directly.
When was the Scientist, Biology job at alector posted?
This Scientist, Biology position at alector was posted on Oct 12, 2026. Apply as soon as possible — early applications are often reviewed first.
Scientist, Biology
alector · 💰 USD 145K–155K
You'll be redirected to alector's official application page on Lever.