Senior Director, Head of China IT
structuretx
Principal Scientist to Associate Director, Chemistry
structuretx· 221- DU2 Chemistry
About this role
About Us:
Structure Therapeutics develops life‐changing medicines for patients using advanced structure‐based and computational drug discovery technology. The company’s platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical‐stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions.
Structure Therapeutics is led by an experienced group of international drug innovators and financed by top-tier global life sciences investors. The company completed an initial public offering (IPO) in February 2023. With offices in California and Shanghai, Structure Therapeutics has the benefit of being at the center of life science innovation in both the US and China and capitalizing on the strengths of each geographic location.
Position Summary:
Reporting to the Senior Director of Chemistry, this position will be responsible for leading SAR studies of one or more GKAR chemical series to deliver milestones working closely with biology/Sbio/CADD/IP/CRO.
Job Responsibilities:
- As a dynamic chemistry leader, drive and direct medicinal chemistry functions for one or more drug discovery projects, working in concert with cross functional team members.
- Analyze screening data, perform literature reviews, design, propose, and execute medicinal chemistry plans, coordinate chemistry and biology data to support compound progression and patent strategies.
- Supervise and direct synthetic chemistry activities at contract research organizations (CROs).
- Serve as a scientific expert in medicinal chemistry with both internal and external partners and provide recommendations regarding new targets and emerging external opportunities.
Qualifications:
- PhD in Organic or Medicinal Chemistry or its equivalent and 5-10 years industry experience in small molecule medicinal chemistry
- Demonstrated advancement of projects through various stages of drug discovery and delivery of clinical candidates
- Proficiency in complex problem-solving and expert knowledge of modern methods of synthetic/medicinal chemistry
- Familiarity with structure-based drug discovery, experience of working closely with computational chemists as part of project team
- Track record of scientific contributions including peer reviewed publications, patent applications
- Highly motivated, open-minded, results driven individual with excellent organizational, interpersonal and communication skills
Frequently Asked Questions
Is the salary disclosed for the Principal Scientist to Associate Director, Chemistry position at structuretx?
The salary for this Principal Scientist to Associate Director, Chemistry role at structuretx is not publicly listed. Click "Apply Now" to learn more about the compensation package on their official careers page.
Where is the Principal Scientist to Associate Director, Chemistry position at structuretx located?
This Principal Scientist to Associate Director, Chemistry role at structuretx is based in Shanghai, Pudong District, China. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Is the Principal Scientist to Associate Director, Chemistry role at structuretx full-time or part-time?
This is listed as a FTE position. It is posted as a Principal Scientist to Associate Director, Chemistry role in the 221- DU2 Chemistry department at structuretx.
Which team or department does the Principal Scientist to Associate Director, Chemistry at structuretx belong to?
This Principal Scientist to Associate Director, Chemistry position is part of the 221- DU2 Chemistry department at structuretx. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Principal Scientist to Associate Director, Chemistry position at structuretx?
Click the "Apply Now" button on this page. You will be redirected to structuretx's official application portal hosted on bamboohr where you can submit your application directly.
When was the Principal Scientist to Associate Director, Chemistry job at structuretx posted?
This Principal Scientist to Associate Director, Chemistry position at structuretx was posted on Jul 6, 2026. Apply as soon as possible — early applications are often reviewed first.
Principal Scientist to Associate Director, Chemistry
structuretx
You'll be redirected to structuretx's official application page on bamboohr.