Principal Project Manager

lonza· US74 Lonza Manufacturing LLC
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📍 US - Vacaville, CAFull time💰 USD 160K–266K

About this role

 

Location: Vacaville, California

This is a fully site‑based role. Working together in person supports close, real‑time collaboration and the technical precision needed to manufacture medicines to the highest quality and safety standards.

 

The Principal Project Manager (PM), is responsible for managing capital and expense (non-capital) projects at the Vacaville site. This position ensures safe delivery, compliance with all

applicable requirements, including cGMP quality, risk, schedule and budget. The PM shall work closely Global Engineering, and colleagues in Vacaville Facilities and Engineering (F&E),

Manufacturing, Manufacturing Science and Technology (MSAT) Safety Health Environment (SHE) and Quality Departments.

 

What you will get

 

The full-time base annual salary for this position is expected to range between $159,750 to $266,250.  In addition, below you will find a comprehensive summary of the benefits package we offer:

  • Performance-related bonus
  • Medical, dental and vision insurance
  • 401(k) matching plan
  • Life insurance, as well as short-term and long-term disability insurance
  • Employee assistance programs
  • Paid Time Off

  

 

What you will do

 

  • Lead end-to-end delivery of complex cGMP facility modifications, tech transfers, and capital projects from design through commissioning and closeout.
  • Own project performance by strictly managing budgets and meeting milestone schedules for manufacturing upgrades and new construction.
  • Ensure all engineering, construction, and operational activities strictly adhere to federal, state, local, and EHS regulatory requirements.
  • Communicate project objectives, risks, and milestone status with senior management, client teams, procurement, legal, and F&E leadership.
  • Partner with procurement to develop, negotiate, and manage external contracts and internal resources to optimize project delivery.
  • Proactively identify project risks, resolve cross-functional conflicts, and align stakeholder expectations to ensure successful outcomes.
  • Continuously refine project management procedures and ensure full compliance with internal project governance standards.

 

 What we look for

 

  • Bachelor’s Degree in Chemical  or Mechanical Engineering.
  • Proven expertise in end-to-end project execution, spanning scope definition, engineering design, procurement, construction, commissioning, start-up, and closeout.
  • Strong executive accountability for strict budget management, accelerated delivery schedules, and enterprise milestone targets.
  • Executive-level oversight of complex, highly regulated operational environments, ensuring absolute compliance with local, federal, and EHS standards.
  • Exceptional ability to align expectations, communicate risks, and drive strategic alignment with senior leadership, legal, procurement, and client teams.
  • Advanced expertise in orchestrating internal resources and partnering with procurement to negotiate high-value contractor and supplier agreements.
  • Champion of continuous improvement, evolving site-wide project procedures, governance frameworks, and automation infrastructure.

 

About Lonza

 

At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of.

 

Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law.

 

Ready to shape the future of life sciences? Apply now.

Frequently Asked Questions

What is the salary for the Principal Project Manager role at lonza?
The listed salary for this Principal Project Manager position at lonza is USD 160K–266K. This is an Full time role.
Where is the Principal Project Manager position at lonza located?
This Principal Project Manager role at lonza is based in US - Vacaville, CA. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Is the Principal Project Manager role at lonza full-time or part-time?
This is listed as a Full time position. It is posted as a Principal Project Manager role in the US74 Lonza Manufacturing LLC department at lonza.
Which team or department does the Principal Project Manager at lonza belong to?
This Principal Project Manager position is part of the US74 Lonza Manufacturing LLC department at lonza. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Principal Project Manager position at lonza?
Click the "Apply Now" button on this page. You will be redirected to lonza's official application portal hosted on workday where you can submit your application directly.
When was the Principal Project Manager job at lonza posted?
This Principal Project Manager position at lonza was posted on Sep 28, 2026. Apply as soon as possible — early applications are often reviewed first.
Principal Project Manager
lonza · 💰 USD 160K–266K
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