Ultrasound Technologist II
massgeneralbrigham
Post-Doctoral Research Fellow - Gene Editing Therapy
massgeneralbrigham· 5110 Massachusetts Eye and Ear Infirmary
About this role
Site: Massachusetts Eye and Ear Infirmary
Onsite243-245 Charles Street40RegularDay (United States of America)5110 Massachusetts Eye and Ear Infirmary is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
The postdoctoral fellows will function as part of a multi-disciplinary team of scientists and clinicians. Responsibilities include participating in all aspects of data acquisition and management; developing, modifying, and executing analytical protocols; preparing publications and scientific presentations; disseminating results in peer-reviewed scientific journals and at major national and international meetings, and mentoring junior staff. Opportunities exist for excellent scientific interactions and collaborations with an extensive program of seminars, symposia, and other meetings focused on a large array of topics in clinical research and related technology.
Qualifications
We are seeking postdoctoral fellows to work on gene and editing therapy for genetic hearing loss and advancing our findings toward clinical applications. Our gene and editing therapies have successfully restored hearing in multiple mouse models (Gao et al., Nature, 2017; Du et al., Mol Ther, 2023; Yong et al., Nat Commun, 2023; Zhu et al., Sci Transl Med, 2024; Wei et al., JCI, 2025). The projects include the development of new technologies (e.g. RNA editing, epigenetic modifications, shRNA) for different forms of genetic hearing loss and multiple IND-enabling studies for gene and editing therapies with the goals to initiate clinical trials in 3 years. The work is supported by the NIH SCGE program (https://scge.mcw.edu/ind-enabling-studies-multiple-disease-platforms/).
Our laboratory employs state-of-the-art technologies, including in vitro adult cochlea explant culture, reprogramming, scRNAseq, inner ear organoids, genome editing, gene therapy, viral and non-viral delivery, and physiological function analysis. We are collaborating with the industry, working with CROs and interacting with the FDA to bring our work towards the clinic.
We are pioneers in clinical translational applications, having conducted the first successful OTOF gene therapy trial in children born with complete hearing loss, resulting in restored hearing and speech capabilities (Lv et al., The Lancet, 2024; Wang et al., Nat Med, 2024).
Our lab is part of Eaton-Peabody Laboratories, the largest hearing research center globally, renowned for its diverse research programs in hearing science. We offer a unique and exciting opportunity for candidates interested in advancing basic research to translational applications, including human studies.
Candidate Requirements: We seek individuals with a Ph.D., M.D./Ph.D., or M.D. For gene/editing therapy, we seek candidates with a strong background in genetic hearing loss, in vivo animal inner ear study, AAV-mediated gene therapy and editing technology. A strong track record of scientific publications is essential.
Salary: $71,750.00 - $73,544.00/Annual
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EEO Statement:
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
Frequently Asked Questions
What is the salary for the Post-Doctoral Research Fellow - Gene Editing Therapy role at massgeneralbrigham?
The listed salary for this Post-Doctoral Research Fellow - Gene Editing Therapy position at massgeneralbrigham is USD 72K–74K. This is an Full time role.
Where is the Post-Doctoral Research Fellow - Gene Editing Therapy position at massgeneralbrigham located?
This Post-Doctoral Research Fellow - Gene Editing Therapy role at massgeneralbrigham is based in Boston-MA. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Is the Post-Doctoral Research Fellow - Gene Editing Therapy role at massgeneralbrigham full-time or part-time?
This is listed as a Full time position. It is posted as a Post-Doctoral Research Fellow - Gene Editing Therapy role in the 5110 Massachusetts Eye and Ear Infirmary department at massgeneralbrigham.
Which team or department does the Post-Doctoral Research Fellow - Gene Editing Therapy at massgeneralbrigham belong to?
This Post-Doctoral Research Fellow - Gene Editing Therapy position is part of the 5110 Massachusetts Eye and Ear Infirmary department at massgeneralbrigham. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Post-Doctoral Research Fellow - Gene Editing Therapy position at massgeneralbrigham?
Click the "Apply Now" button on this page. You will be redirected to massgeneralbrigham's official application portal hosted on workday where you can submit your application directly.
When was the Post-Doctoral Research Fellow - Gene Editing Therapy job at massgeneralbrigham posted?
This Post-Doctoral Research Fellow - Gene Editing Therapy position at massgeneralbrigham was posted on Oct 1, 2026. Apply as soon as possible — early applications are often reviewed first.
Post-Doctoral Research Fellow - Gene Editing Therapy
massgeneralbrigham · 💰 USD 72K–74K
You'll be redirected to massgeneralbrigham's official application page on Workday.