Operational Excellence - Sr. Manager

thermofisher· 27-3435995 Patheon Biologics LLC
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📍 St. Louis, Missouri, USAFull time

About this role

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Office

Job Description

Move fast. Think big. Make an impact that can change lives. 

 

At Thermo Fisher Scientific’s St. Louis site, we move with urgency because what we do matters. Every day, our teams are helping turn breakthrough science into biologic medicines for patients around the world—and behind every batch, every decision and every challenge we solve is a patient waiting for what we make. 

 

This is a fast-paced, high-energy environment where science, technology and talented people come together to do extraordinary work. Whether you’re in manufacturing, quality, engineering, the lab or a support function, you are part of the mission. Your expertise matters. Your ideas matter. Your ability to move quickly, solve problems and deliver matters. 

 

DESCRIPTION 

As a Senior Manager of PPI Business System at Thermo Fisher Scientific, you will facilitate transformational change and continuous improvement across the organization. Leading the implementation of our Practical Process Improvement (PPI) Business System, you will partner with business leaders to establish and mature lean management practices that enable profitable growth, enhance customer experience, and increase employee engagement. Through strategic deployment, coaching, and hands-on facilitation of improvement initiatives, you will help develop a problem-solving culture focused on operational excellence. You'll collaborate with cross-functional teams to streamline processes, eliminate waste, and deliver measurable results in quality, productivity, and customer satisfaction. 

 

As a strategic partner, coach, and hands-on improvement leader, you will help build a culture of continuous improvement and structured problem solving. You will work across functions and organizational levels to identify improvement opportunities, facilitate high-impact initiatives, develop organizational capability, and ensure improvements deliver measurable and sustainable business results. 

 

REQUIREMENTS 

  • Advanced Degree plus 6 years of experience, or Bachelor's Degree plus 8 years of experience in lean leadership implementing continuous improvement initiatives 
  • Hands on experience in operational excellence, lean, continuous improvement, or PPI in a complex operational or manufacturing environment.  
  • Lean Six Sigma Black Belt required 
  • Project Management Professional (PMP) certification a plus 
  • Demonstrated experience developing and deploying PPI/lean tools including: 
  • Strategy deployment and value stream mapping 
  • Tiered daily management systems and leader standard work 
  • Kaizen facilitation and problem-solving methodologies 
  • Standard work, error-proofing, and visual management 
  • Strong financial and business acumen with ability to identify, quantify and track improvement opportunities 
  • Excellent communication, presentation and influence skills to engage all organizational levels 
  • Demonstrated success coaching and developing continuous improvement capabilities in others 
  • Experience leading change initiatives in a matrix organization 
  • Strong project management skills and ability to manage multiple priorities 
  • Ability to travel up to 20% 
  • Manufacturing/operations experience preferred 
  • Expertise in data analytics and performance metrics 
  • Proficiency in Microsoft Office suite required 
  • Commitment to driving improvement and leading transformational change 
  • Ability to work effectively across functions without direct authority 
  • Experience in regulated industry (e.g., life sciences, medical devices) preferred 

 

 

Compensation & Benefits  

We offer competitive compensation and a comprehensive Total Rewards package designed to support your health, wellbeing, financial security and life outside of work. Benefits include medical, dental and vision coverage, retirement and savings programs, paid time off, wellbeing resources, business resource groups, career development opportunities and additional programs to support you and your family.  

  

Compensation will be determined based on factors including experience, skills, education, internal equity, geographic location and other job-related considerations.   

 Because when you’re helping us deliver for patients, we want to help you thrive—at work and beyond.  

  

Other

Relocation assistance is not provided.

Must be legally authorized to work in the United States now and in the future, without sponsorship.

Must be able to pass a comprehensive background check, which includes a drug screening.

 

 


Frequently Asked Questions

Is the salary disclosed for the Operational Excellence - Sr. Manager position at thermofisher?
The salary for this Operational Excellence - Sr. Manager role at thermofisher is not publicly listed. Click "Apply Now" to learn more about the compensation package on their official careers page.
Where is the Operational Excellence - Sr. Manager position at thermofisher located?
This Operational Excellence - Sr. Manager role at thermofisher is based in St. Louis, Missouri, USA. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Is the Operational Excellence - Sr. Manager role at thermofisher full-time or part-time?
This is listed as a Full time position. It is posted as a Operational Excellence - Sr. Manager role in the 27-3435995 Patheon Biologics LLC department at thermofisher.
Which team or department does the Operational Excellence - Sr. Manager at thermofisher belong to?
This Operational Excellence - Sr. Manager position is part of the 27-3435995 Patheon Biologics LLC department at thermofisher. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Operational Excellence - Sr. Manager position at thermofisher?
Click the "Apply Now" button on this page. You will be redirected to thermofisher's official application portal hosted on workday where you can submit your application directly.
When was the Operational Excellence - Sr. Manager job at thermofisher posted?
This Operational Excellence - Sr. Manager position at thermofisher was posted on Sep 24, 2026. Apply as soon as possible — early applications are often reviewed first.
Operational Excellence - Sr. Manager
thermofisher
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