Manager, Commercial Accounting

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🌍 Remote📍 US Remote💰 USD 134K–145K

About this role

“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone.  Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor.  Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”

Mineralys is a fully remote company.

Manager, Commercial Accounting

The Manager, Commercial Accounting will be responsible for overseeing accounting activities related to product revenue, gross-to-net reserves, accounts receivable, inventory and cost of goods sold, and other commercial related accounting processes. The role will partner closely with Trade & Distribution, Market Access, CMC, and third-party partners to ensure accurate financial reporting and support commercialization efforts.  The Manager will also be responsible for identifying and driving process improvement.

Key Responsibilities:

Revenue Accounting & Month-End Close

  • Manage the monthly close process related to product revenue, gross-to-net reserves, accounts receivable, and related commercial accounting activities.
  • Prepare and review journal entries, account reconciliations, and supporting schedules for revenue-related accounts.
  • Ensure revenue recognition is recorded in accordance with ASC 606.
  • Maintain accurate documentation supporting revenue accounting conclusions and estimates.

Inventory & Cost Accounting

  • Manage monthly close activities related to inventory and cost of goods sold.
  • Oversee inventory accounting activities, including inventory valuation, inventory reserves, inventory reconciliations, and related accounting analyses.
  • Review inventory reports and activity received from third-party logistics providers (3PLs) and ensure accurate recording of inventory transactions.
  • Monitor inventory movements, adjustments, write-offs, product returns, and related reserve calculations.
  • Partner with Trade and Distribution, CMC, and external partners to investigate and resolve inventory discrepancies.
  • Support physical inventory count procedures and related reconciliations performed by third-party providers.

Gross-to-Net Accounting

  • Prepare and maintain gross-to-net reserve calculations, including rebates, chargebacks, returns, prompt pay discounts, distribution service fees, copay assistance programs, and other commercial deductions.
  • Collaborate with Market Access, Government Pricing, and Commercial teams to ensure accurate reserve methodologies and assumptions.
  • Perform periodic actual-to-estimate analyses and recommend adjustments to reserve methodologies as needed.

Accounts Receivable & Order-to-Cash

  • Serve as the primary accounting liaison with third-party logistics providers (3PLs), distributors, and other commercial partners, ensuring timely and accurate transaction processing and reporting.
  • Oversee third-party managed order-to-cash activities, including product sales, invoicing, collections, cash applications, deductions, and dispute resolution.
  • Ensure timely reconciliation of accounts receivable balances, including oversight of information received from 3PLs and commercial partners.
  • Review customer balances, aging reports, collection activities, and related reporting provided by commercial partners and third-party service providers.
  • Support the evaluation of customer credit risk, credit limits, and related mitigation strategies in coordination with commercial and finance leadership.

Commercial and Launch Support

  • Partner with Market Access, CMC and Trade & Distribution teams to support commercialization initiatives and product launches.
  • Assist in the design and implementation of processes and controls supporting new distribution channels, customer programs, and launch activities.
  • Support contract reviews and assess accounting implications of commercial arrangements.

Financial Reporting & Compliance

  • Prepare schedules and analyses supporting quarterly and annual financial reporting requirements.
  • Assist with external audits and regulatory reporting requirements.
  • Develop and maintain policies, procedures, and accounting documentation related to revenue accounting.
  • Support SOX compliance efforts, including control execution, documentation, and remediation activities.

Process Improvement & Systems

  • Identify opportunities to improve efficiency, automation, reporting, and data analytics across the revenue accounting cycle.
  • Participate in ERP implementation, system enhancements, and integration projects.

Leadership & People Management

  • manage, mentor, and develop team member while fostering accountability, collaboration, and professional growth.

 

Qualifications:

Required

  • Bachelor's degree in Accounting or Finance. CPA preferred.
  • 8+ years of progressive accounting experience, including experience in supporting commercial accounting activities in the biotechnology, pharmaceutical or life sciences industry.
  • Strong understanding of US GAAP, including ASC 606 revenue recognition, gross-to-net, inventory and cost of goods sold accounting
  • Strong understanding of pharmaceutical order-to-cash processes and related accounting activities, including accounts receivable, deductions, customer reconciliations.
  • Experience supporting inventory accounting in a commercial-stage biotechnology, pharmaceutical, or life sciences company.
  • Experience working with third-party logistics providers (3PLs), wholesalers, and other commercial service providers.
  • Experience with month-end close, account reconciliations, and financial reporting.
  • Experience with NetSuite or other large ERP systems.
  • Advanced Microsoft Excel skills.

Preferred

  • Public accounting experience and/or publicly traded company experience
  • Experience supporting SOX compliance and internal controls.

Knowledge, Skills & Abilities

  • Excellent analytical, problem-solving, and critical-thinking skills.
  • Strong attention to detail and ability to manage multiple priorities.
  • Effective communication and cross-functional collaboration skills.
  • Proven ability to work independently in a fast-paced, dynamic environment.
  • Continuous improvement mindset with a focus on scalability, automation, and operational excellence.

Travel

This position requires up to 10% travel. Frequently travel is outside the local area and overnight. 

US Salary Range: $134,000 to $145,000

#LI-Remote

 

Frequently Asked Questions

What is the salary for the Manager, Commercial Accounting role at mineralystherapeutics?
The listed salary for this Manager, Commercial Accounting position at mineralystherapeutics is USD 134K–145K. This is a remote full-time role.
Is the Manager, Commercial Accounting job at mineralystherapeutics remote?
Yes, this Manager, Commercial Accounting position at mineralystherapeutics is remote, with team members based in US Remote. You can work from home or anywhere in the supported regions.
Which team or department does the Manager, Commercial Accounting at mineralystherapeutics belong to?
This Manager, Commercial Accounting position is part of the Finance department at mineralystherapeutics. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Manager, Commercial Accounting position at mineralystherapeutics?
Click the "Apply Now" button on this page. You will be redirected to mineralystherapeutics's official application portal hosted on greenhouse where you can submit your application directly.
When was the Manager, Commercial Accounting job at mineralystherapeutics posted?
This Manager, Commercial Accounting position at mineralystherapeutics was posted on Oct 1, 2026. Apply as soon as possible — early applications are often reviewed first.
Manager, Commercial Accounting
mineralystherapeutics · 💰 USD 134K–145K
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You'll be redirected to mineralystherapeutics's official application page on Greenhouse.