Machine Learning Engineer

latent· Engineering
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📍 San FranciscoFullTime💰 USD 225K–300K

About this role

About Latent

Latent is the enterprise pharmacy intelligence platform, powered by a clinical agentic engine, that enables health systems to grow their pharmacy operations and serve more patients. One engine works across the pharmacy journey to identify patients who qualify for care, improve medication access, capture eligible prescriptions and support patients throughout treatment. Latent’s platform enables more than 60 leading health systems that collectively serve an estimated 70 million people. Founded by Sriram “Sri” Somasundaram and Rishabh Jain, Latent has raised $80 million from Transformation Capital, Spark Capital, Conviction, General Catalyst, Y Combinator, and others.

 

The Role

The Machine Learning team is responsible for building systems that run in real clinical workflows. We work on verifiable reinforcement learning at scale, mid-training and post-training of foundation models, and novel objectives derived from longitudinal patient data. We are a small group of researchers and engineers focused on pushing the frontier while shipping real systems into production, and we expect engineers to take ownership of critical systems, not components.

As a Machine Learning Engineer, you will own the design, development, and operation of production-grade ML systems that run in real clinical workflows. You will drive systems from ambiguous problem definition through to reliable production deployment, setting technical direction along the way. We are primarily hiring for senior and staff-level engineers who are comfortable owning critical systems end-to-end. This role involves owning systems that directly impact real patient outcomes.

 

What You'll Do

  • Own end-to-end ML systems, including architecture, data, modeling, evaluation, and production infrastructure

  • Train and fine-tune large language models (LLMs) for:

    • Clinical reasoning

    • Medical question answering

    • Evidence-grounded generation

  • Make and own tradeoffs across accuracy, latency, cost, and safety in high-stakes production environments

  • Develop evaluation frameworks to ensure model safety and clinical validity

  • Integrate ML systems into product workflows and patient-facing applications

  • Monitor system performance in production and iterate based on real-world usage and feedback

  • Define what “correct” means in ambiguous clinical workflows in collaboration with engineers and clinicians

 

What We're Looking For

  • Strong foundation in machine learning and software engineering

  • Track record of building and owning ML systems in production where performance, reliability, or correctness materially mattered

  • Experience driving ambiguous ML problems from 0→1, including problem formulation, model design, and productionization

  • Hands-on experience with PyTorch or similar frameworks

  • Ability to operate independently in high-ambiguity environments with minimal guidance

  • Strong product and engineering judgment — you know when to use ML, when not to, and how to scope problems accordingly

  • Comfort working in a fast-moving, early-stage environment

  • Experience working on systems where decisions have real-world consequences (e.g., healthcare, finance, infrastructure)

Nice to Have

  • Experience deploying LLMs in production environments

  • Experience building distributed systems or large-scale data pipelines

  • Experience working with clinical, biomedical, or other regulated datasets

 

Why Join Latent

  • Backed by top-tier investors including General Catalyst, Conviction, and Y Combinator

  • Work alongside a high-caliber team building products our healthcare partners love

  • Work on mission-critical problems at the intersection of AI and healthcare

  • Real ownership and visibility

  • High-impact role on a small, fast-growing team

Benefits

  • Competitive compensation, including meaningful equity

  • Medical, dental, and vision insurance for employee and dependents

  • Flexible PTO policy

  • Paid parental leave

  • Fertility and family-building stipend through Carrot

Frequently Asked Questions

What is the salary for the Machine Learning Engineer role at latent?
The listed salary for this Machine Learning Engineer position at latent is USD 225K–300K. This is an FullTime role.
Where is the Machine Learning Engineer position at latent located?
This Machine Learning Engineer role at latent is based in San Francisco. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Is the Machine Learning Engineer role at latent full-time or part-time?
This is listed as a FullTime position. It is posted as a Machine Learning Engineer role in the Engineering department at latent.
Which team or department does the Machine Learning Engineer at latent belong to?
This Machine Learning Engineer position is part of the Engineering department at latent. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Machine Learning Engineer position at latent?
Click the "Apply Now" button on this page. You will be redirected to latent's official application portal hosted on ashby where you can submit your application directly.
When was the Machine Learning Engineer job at latent posted?
This Machine Learning Engineer position at latent was posted on Sep 29, 2026. Apply as soon as possible — early applications are often reviewed first.
Machine Learning Engineer
latent · 💰 USD 225K–300K
Apply for this role ↗

You'll be redirected to latent's official application page on Ashby ATS.