Director Clinical Bioinformatics

illumina· US14 Illumina Software Inc.
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📍 US - California - San DiegoFull time💰 USD 205K–308K

About this role

What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Illumina is seeking a Director of Clinical Bioinformatics to lead delivery of informatic solutions that power Illumina’s end-to-end solutions and assay informatics. We are looking for an experienced bioinformatics leader that is passionate about powering new applications with innovative new informatics approaches using Illumina sequencing and multi-omic technologies. This is a unique opportunity to be a core contributor to Illumina’s mission to unlock the power of the genome by creating our next application solutions and industry leading bioinformatic algorithms. 

Location: The ideal candidate is based in San Diego, CA or within California with the ability to travel to San Diego on a regular 

basis. 

Responsibilities 

• Lead bioinformatics for design, delivery, and validation of end-to-end assay and application solutions.  

• Innovate vigorously to deliver high value solutions to drive next wave of precision medicine and multi-omics applications 

• Responsible for design and implementation of novel bioinformatics algorithms on the DRAGEN platform 

• Build and manage relationships with external customers, partners, and key opinion leaders and represent Illumina externally 

• Develop program to proactively monitor, and tactically and strategically respond to competitive technologies  

Requirements 

• Typically requires a Bachelor’s degree and a minimum of 18 years of related experience, with 10+ years of Management experience.

• Proven track record of successfully leading major multi-disciplinary product development projects from concept to commercial release 

• Extensive experience developing Bioinformatics algorithms for multiple technologies (NGS and microarray) and domain areas (oncology, genetics, and reproductive health) 

• Broad experience building regulated lab developed tests, distributed IVD products, or regulated instrument systems 

• Must effectively balance innovation roadmap with execution-oriented product development projects 

• Exceptional communication skills  

• Able to deliver result in uncertain and fast-paced environment  

• Results oriented leader with 5+ years leading globally distributed teams; must have experience managing managers 

 

#LI-REMOTE

 

 

The estimated base salary range for the Director Clinical Bioinformatics role based in the United States of America is: $205,100 - $307,700. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.


We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.

Frequently Asked Questions

What is the salary for the Director Clinical Bioinformatics role at illumina?
The listed salary for this Director Clinical Bioinformatics position at illumina is USD 205K–308K. This is an Full time role.
Where is the Director Clinical Bioinformatics position at illumina located?
This Director Clinical Bioinformatics role at illumina is based in US - California - San Diego. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Is the Director Clinical Bioinformatics role at illumina full-time or part-time?
This is listed as a Full time position. It is posted as a Director Clinical Bioinformatics role in the US14 Illumina Software Inc. department at illumina.
Which team or department does the Director Clinical Bioinformatics at illumina belong to?
This Director Clinical Bioinformatics position is part of the US14 Illumina Software Inc. department at illumina. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Director Clinical Bioinformatics position at illumina?
Click the "Apply Now" button on this page. You will be redirected to illumina's official application portal hosted on workday where you can submit your application directly.
When was the Director Clinical Bioinformatics job at illumina posted?
This Director Clinical Bioinformatics position at illumina was posted on Sep 17, 2026. Apply as soon as possible — early applications are often reviewed first.
Director Clinical Bioinformatics
illumina · 💰 USD 205K–308K
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You'll be redirected to illumina's official application page on Workday.